Skip to content

Latest commit

 

History

History
37 lines (26 loc) · 1.52 KB

README.md

File metadata and controls

37 lines (26 loc) · 1.52 KB

MDR-hvKp

The spread of antimicrobial-resistant bacteria globally is a pressing issue that has captured my attention.

  • It's concerning to see how certain bacteria are becoming resistant to the drugs we use to treat them, leading to the rise of superbugs that are difficult to control.

  • In 2017, WHO Priority Pathogens: A list of antibiotic-resistant bacteria assessed to be of highest priority for new antibiotic development.

  • In 2019, nearly 1.3 million deaths including 140 thousand newborns were caused by AMR. This is expected to rise to 10 million deaths by 2050.

  • We can develop strategies to prevent antimicrobial spread and improve patient outcomes by understanding the patterns and drivers of antimicrobial resistance.

R package requirements:

  • R 4.1.0
  • shiny 1.6.0
  • shinydashboard 0.7.2
  • DT 0.19
  • dplyr 1.0.7
  • ggplot2 3.3.5
  • plotly 4.9.4.1
  • heatmaply 1.5.0
  • paletteer 1.5.0
  • gtsummary 1.7.2
  • rmarkdown 2.25
  • renv 1.0.3

Features:

This web-based application has been developed to facilitate the exploration of genomic diversity and population structure analysis of multi-drug resistant hypervirulent Klebsiella pneumoniae (MDR-hvkp).

The application is designed to provide a user-friendly interface for researchers and clinicians to analyze and visualize the genomic data of MDR-hvkp strains.

It offers a range of tools and features to help users identify genetic variations, track the pathogen's spread, and understand the population structure of MDR-hvkp.

Authors

Julio Cesar - 2023, Beijing